Hi,
Thanks for sharing this problem.
This is caused by NCrunch failing to correctly detect the versions of .NET stored on your system. I thinks that .NET v4.6.2 is installed, though based on the error you've shown, this doesn't look to be the case.
Would you be able to check something for me in your registry? I need to know the value of the following registry key:
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\NET Framework Setup\NDP\v4\Full\Release
Installing .NET v4.6.2 will solve this problem. The problem is not related to the version of the framework you are using for your projects (NCrunch will still use v4.6.1 for these projects). This is coming from the engine host itself.