Thanks Remco,
I Unblocked the nCrunch.VSIntegration2017.dll file, in order to get Visual Studio to load NCrunch properly without causing an exception. 
However, I'm seeing this for every project in the NCrunch Tests tab:
nCrunch.TaskRunner.Ipc.IpcConnectionClosedException: The connection has been closed
   at nCrunch.Core.ProcessManagement.ExternalProcessManager.(ProcessorArchitecture , ProcessLoadParameters )
   at nCrunch.Core.ProcessManagement.ExternalProcessManager.LoadExternalProcess(ProcessLoadParameters parameters, GridClientId client)
   at nCrunch.Core.BuildManagement.BuildProcessLauncher..()
   at nCrunch.Common.PerformanceTracking.PerfTracker.TryTrackActivity(String name, Action activity)
   at nCrunch.Core.BuildManagement.BuildProcessLauncher.(Action`1 , ProcessorArchitecture , GridClientId , BuildSystemParameters , IList`1 )
   at nCrunch.Core.BuildManagement.BuildProcessLauncher.AnalyseComponentBuildInExternalProcess(ComponentLoadParameters parameters, IList`1 customEnvironmentVariables)
   at nCrunch.Client.ComponentLoader.SnapshotComponentLoader.(ProcessorArchitecture , String )
   at nCrunch.Client.ComponentLoader.SnapshotComponentLoader.CreateComponentFromXml(FilePath projectFilePath, ParsedBuildXml projectXml, FilePath solutionFilePath, String[] additionalFilesToIncludeAtSolutionLevel, Boolean isLoadedFromFile, VisualStudioVersion vsVersion, ComponentUniqueName componentName, TaskSettings componentTaskSettings, Exception parseException, String targetFramework)
Is there anything I can do to get NCrunch running with this build, or is it unstable?