.vcxproj files still make use of the same (or at least very similar) syntax in order to include source files, for example:
<ItemGroup>
<ClInclude Include="ClrCpp.h" />
<ClInclude Include="resource.h" />
<ClInclude Include="Stdafx.h" />
</ItemGroup>
<ItemGroup>
<ClCompile Include="AssemblyInfo.cpp" />
<ClCompile Include="ClrCpp.cpp" />
<ClCompile Include="Stdafx.cpp">
<PrecompiledHeader Condition="'$(Configuration)|$(Platform)'=='Debug|Win32'">Create</PrecompiledHeader>
<PrecompiledHeader Condition="'$(Configuration)|$(Platform)'=='Release|Win32'">Create</PrecompiledHeader>
</ClCompile>
</ItemGroup>
<ItemGroup>
<None Include="app.ico" />
<None Include="ReadMe.txt" />
</ItemGroup>
NCrunch is able to identify these dependencies in the same way as for C#/VB dependencies, so in theory as long as the file is showing in the VS solution explorer, then NCrunch should be aware of it and no custom configuration should be necessary.