This issue seems as though it may be similar to an earlier reported issue related to TypeMock Isolator V7:
http://forum.ncrunch.net...g-with-isolator-V7.aspx
The residence of the TMockRunner.exe processes indicates that NCrunch is correctly loading the Isolator profiler into the task runner, so most likely the is something happening within the profiler that is causing it to fail in the environment.
Unfortunately the Isolator profiler is very much a black box to NCrunch (and myself), so there's no way for me to help you with identifying the true source of the problem. Earlier versions of Isolator V7 did have reported problems with NCrunch, although these were confirmed to be fixed in a recent release. It may be that the build of Isolator you are using has a regression, or that the environment you're working in is somehow surfacing a different issue.
Something to try could be to downgrade to the version of Isolator V7 which was confirmed to be working with NCrunch. This would help to confirm whether the issue is caused by a regression or whether it's something in your environment.